In a large pot, melt the butter over medium heat. Add the minced garlic and red pepper flakes, cooking until the garlic is fragrant but not browned, about 1-2 minutes.
Pour in the white wine and lemon juice, stirring to combine. Bring the mixture to a simmer.
Add the clams to the pot, cover, and cook for 5-7 minutes, or until the clams have opened. Discard any clams that remain closed.
Stir in the chopped parsley and season with salt and pepper to taste.
Serve the clams in bowls with the broth, garnished with additional parsley and lemon wedges on the side.